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Article

AMP-Activated Protein Kinase Alpha 2 Deletion Induces VSMC Phenotypic Switching and Reduces Features of Atherosclerotic Plaque Stability.

Circulation research - 2 Sept 2016

Ding Ye, Zhang Miao, Zhang Wencheng, Lu Qiulun, Cai Zhejun, Song Ping, Okon Imoh Sunday, Xiao Lei, Zou Ming-Hui

Abstract excerpt

RATIONALE: AMP-activated protein kinase (AMPK) has been reported to play a protective role in atherosclerosis. However, whether AMPKα2 controls atherosclerotic plaque stability remains unknown. OBJECTIVE: The aim of this study was to evaluate the impact of AMPKα2 deletion on atherosclerotic plaque stability in advanced atherosclerosis at the brachiocephalic arteries and to elucidate the underlying mechanisms....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 27439892
DOI: 10.1161/CIRCRESAHA.116.308689
PMCID: PMC6265658

Genes

KLF4

Provenance

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