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Article

Clonal Characteristics of Circulating B Lymphocyte Repertoire in Primary Biliary Cholangitis.

Journal of immunology (Baltimore, Md. : 1950) - 1 Sept 2016

Tan Yan-Guo, Wang Yu-Qi, Zhang Ming, Han Ying-Xin, Huang Chun-Yang, Zhang Hai-Ping, Li Zhuo-Min, Wu Xiao-Lei, Wang Xiao-Feng, Dong Yan, Zhu Hong-Mei, Zhu Shi-da, Li Hong-Mei, Li Ning, Yan Hui-Ping, Gao Zu-Hua

Abstract excerpt

Primary biliary cholangitis (PBC) is an autoimmune liver disease characterized by elevated serum anti-mitochondrial Ab and lymphocyte-mediated bile duct damage. This study was designed to reveal the clonal characteristics of B lymphocyte repertoire in patients with PBC to facilitate better understanding of its pathogenesis and better management of these patients. Using high-throughput sequencing of Ig genes, we...

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PMID: 27430717
DOI: 10.4049/jimmunol.1600096

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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