Article
Clinical significance of autoantibodies in primary biliary cirrhosis.
Seminars in liver disease - 1 Aug 2014
Nakamura Minoru
Abstract excerpt
Antimitochondrial, anti-gp210, anti-sp100, and anticentromere antibodies are specifically detected in primary biliary cirrhosis (PBC). In clinical practice, they are useful for the diagnosis of PBC or for evaluating disease severity, clinical phenotype, and long-term outcome. In the typical or classical form of PBC which shows slow progressive loss of small bile ducts with a parallel increase in liver fibrosis,...
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