Article

Autoantibodies in Primary Biliary Cholangitis: From Classical Markers to Emerging Targets

2025-10-28

Abstract excerpt

Primary biliary cholangitis (PBC) is a chronic autoimmune liver disease characterized by progressive destruction of intrahepatic bile ducts. Autoantibodies, particularly anti-mitochondrial antibodies (AMA) and antinuclear antibodies (ANA), are central to diagnosis, prognosis, and pathogenesis. This review provides a comprehensive overview of classical and emerging autoantibodies associated with PBC, including AMA-...

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Literature Corpus work: 09ece5f4-9cc2-5dc9-a6de-bd513f4384fd
DOI: 10.20944/preprints202510.2125.v1

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