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Article

CD19+CD24hiCD38hi B Cell Dysfunction in Primary Biliary Cholangitis

10 Feb 2020

Abstract excerpt

CD19+CD24hiCD38hi B cells are immature transitional B cells that, in normal individuals, exert suppressive effects by IL-10 production but are quantitatively altered and/or functionally impaired in individuals with various autoimmune diseases. Primary biliary cholangitis (PBC), an autoimmune disease, clinically presents as chronic cholestasis and nonsuppurative destructive cholangitis. A role for...

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PMID: 32104147
DOI: 10.1155/2020/3019378

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