Article
The Role of B Cells in Adult and Paediatric Liver Injury.
Frontiers in immunology - 1 Jan 2021
Patel Arzoo M, Liu Yuxin S, Davies Scott P, Brown Rachel M, Kelly Deirdre A, Scheel-Toellner Dagmar, Reynolds Gary M, Stamataki Zania
Abstract excerpt
B lymphocytes are multitasking cells that direct the immune response by producing pro- or anti-inflammatory cytokines, by presenting processed antigen for T cell activation and co-stimulation, and by turning into antibody-secreting cells. These functions are important to control infection in the liver but can also exacerbate tissue damage and fibrosis as part of persistent inflammation that can lead to end stage...
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