Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Clinical Streptococcus pneumoniae isolates induce differing CXCL8 responses from human nasopharyngeal epithelial cells which are reduced by liposomes.

BMC microbiology - 19 Jul 2016

Baumgartner Denja, Aebi Suzanne, Grandgirard Denis, Leib Stephen L, Draeger Annette, Babiychuk Eduard, Hathaway Lucy J

Abstract excerpt

BACKGROUND: Streptococcus pneumoniae causes several human diseases, including pneumonia and meningitis, in which pathology is associated with an excessive inflammatory response. A major inducer of this response is the cholesterol dependent pneumococcal toxin, pneumolysin. Here, we measured the amount of inflammatory cytokine CXCL8 (interleukin (IL)-8) by ELISA released by human nasopharyngeal epithelial (Detroit...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bacterial Capsules
Share to Cholesterol

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Interleukin-8

Share to Liposomes

Share to Nasopharynx

Share to Sphingomyelins

Share to Streptococcus pneumoniae

Share to Streptolysins

Source

Open in PubMed Open full text

Identifiers

PMID: 27430279
DOI: 10.1186/s12866-016-0777-5
PMCID: PMC4950757

Genes

CXCL8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Clinical Streptococcus pneumoniae isolates induce differing CXCL8 responses from human nasopharyngeal epithelial cells which are reduced by liposomes.PMID 27430279Read ↗

Pneumolysin suppresses the initial macrophage pro‐inflammatory response to Streptococcus pneumoniaeSemantic proximity Read ↗

Pneumococcal Extracellular Vesicles Modulate Host Immunity.Semantic proximity Read ↗

The NLRP3 inflammasome is differentially activated by pneumolysin variants and contributes to host defense in pneumococcal pneumonia.Semantic proximity Read ↗

Detoxified pneumolysin derivative Plym2 directly protects against pneumococcal infection via induction of inflammatory cytokines.Semantic proximity Read ↗

Recognition of pneumolysin by Toll-like receptor 4 confers resistance to pneumococcal infection.Semantic proximity Read ↗

Streptococcus pneumoniae evades human dendritic cell surveillance by pneumolysin expression.Semantic proximity Read ↗

Immunostimulation with Macrophage-Activating Lipopeptide-2 Increased Survival in Murine PneumoniaSemantic proximity Read ↗

TLR2-dependent recognition of Streptococcus suis is modulated by the presence of capsular polysaccharide which modifies macrophage responsivenessSemantic proximity Read ↗

The cholesterol-dependent cytolysin pneumolysin from Streptococcus pneumoniae binds to lipid raft microdomains in human corneal epithelial cells.Semantic proximity Read ↗

Toll-like receptor 2-dependent protection against pneumococcal carriage by immunization with lipidated pneumococcal proteins.Semantic proximity Read ↗

Streptococcus gordonii lipoproteins induce IL-8 in human periodontal ligament cells.Semantic proximity Read ↗

Comparison of Lipoteichoic Acid from Different Serotypes of Streptococcus pneumoniaeSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.