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Article

Toll-like receptor 2-dependent protection against pneumococcal carriage by immunization with lipidated pneumococcal proteins.

Infection and immunity - 1 May 2014

Moffitt Kristin, Skoberne Mojca, Howard Angela, Gavrilescu L Cristina, Gierahn Todd, Munzer Scott, Dixit Bharat, Giannasca Paul, Flechtner Jessica Baker, Malley Richard

Abstract excerpt

Infections with Streptococcus pneumoniae cause substantial morbidity and mortality, particularly in children in developing nations. Polysaccharide-conjugate vaccines provide protection against both invasive disease and colonization, but their use in developing countries is limited by restricted serotype coverage and expense of manufacture. Using proteomic screens, we recently identified several antigens that...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 24614661
DOI: 10.1128/IAI.01632-13
PMCID: PMC3993436

Genes

TLR2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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