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Article

Streptococcus pneumoniae evades human dendritic cell surveillance by pneumolysin expression.

EMBO molecular medicine - 1 Jul 2009

Littmann Marie, Albiger Barbara, Frentzen Anne, Normark Staffan, Henriques-Normark Birgitta, Plant Laura

Abstract excerpt

Dendritic cells (DCs) protect the respiratory epithelium via induction of innate immune responses and priming of naïve T cells during the initiation of adaptive immunity. Streptococcus pneumoniae, a commonly carried asymptomatic member of the human nasopharyngeal microflora, can cause invasive and inflammatory diseases and the cholesterol-dependent cytotoxin pneumolysin is a major pneumococcal virulence factor...

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Identifiers

PMID: 20049723
DOI: 10.1002/emmm.200900025
PMCID: PMC3378134

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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