Article
B7-H4 expression in human infiltrating ductal carcinoma‑associated macrophages.
Molecular medicine reports - 1 Sept 2016
Liu Lei, Li Dalin, Chen Shuang, Zhao Ran, Pang Da, Li Dianjun, Fu Zhenkun
Abstract excerpt
B7-H4 is a co‑inhibitory molecule of the B7 family, which is expressed on antigen‑presenting cells (APCs) and is able to limit the T‑cell immune response. Macrophages act as professional APCs and are important for immunoregulation of the tumor microenvironment in breast cancer. In order to identify the association between the presence of B7‑H4 on macrophages and infiltrating ductal carcinoma (IDC), the present...
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