Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Identifying Liver Cancer-Related Enhancer SNPs by Integrating GWAS and Histone Modification ChIP-seq Data.

BioMed research international - 1 Jan 2016

Zhang Tianjiao, Hu Yang, Wu Xiaoliang, Ma Rui, Jiang Qinghua, Wang Yadong

Abstract excerpt

Many disease-related single nucleotide polymorphisms (SNPs) have been inferred from genome-wide association studies (GWAS) in recent years. Numerous studies have shown that some SNPs located in protein-coding regions are associated with numerous diseases by affecting gene expression. However, in noncoding regions, the mechanism of how SNPs contribute to disease susceptibility remains unclear. Enhancer elements...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Databases, Nucleic Acid
Share to Databases, Protein

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Enhancer Elements, Genetic

Share to Genome-Wide Association Study

Share to Hep G2 Cells

Share to Histones

Share to Liver Neoplasms

Share to Protein Processing, Post-Translational

Source

Open in PubMed Open full text

Identifiers

PMID: 27429976
DOI: 10.1155/2016/2395341
PMCID: PMC4939323

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Identifying Liver Cancer-Related Enhancer SNPs by Integrating GWAS and Histone Modification ChIP-seq Data.PMID 27429976Read ↗

Identifying causal regulatory SNPs in ChIP-seq enhancers.Semantic proximity Read ↗

Genome-wide enhancer RNA profiling adds molecular links between genetic variation and human cancers.Semantic proximity Read ↗

Genetic and Epigenetic Fine Mapping of Complex Trait Associated Loci in the Human LiverSemantic proximity Read ↗

DiseaseEnhancer: a resource of human disease-associated enhancer catalog.Semantic proximity Read ↗

Integrative analysis of liver-specific non-coding regulatory SNPs associated with the risk of coronary artery disease.Semantic proximity Read ↗

Combinatorial effects of multiple enhancer variants in linkage disequilibrium dictate levels of gene expression to confer susceptibility to common traits.Semantic proximity Read ↗

High-throughput functional dissection of noncoding SNPs with biased allelic enhancer activity for insulin resistance-relevant phenotypes.Semantic proximity Read ↗

Genetic effects on liver chromatin accessibility identify disease regulatory variants.Semantic proximity Read ↗

Functional annotation of colon cancer risk SNPs.Semantic proximity Read ↗

Expanded chromatin accessibility mapping explains genetic variation associated with complex traits in liver.Semantic proximity Read ↗

m6A-SNPs identified by integrating genomic data are associated with the occurrence and prognosis of HCC.Semantic proximity Read ↗

Comprehensive characterization genetic regulation and chromatin landscape of enhancer-associated long non-coding RNAs and their implication in human cancer.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.