Article
Functional annotation of colon cancer risk SNPs.
Nature communications - 30 Sept 2014
Yao Lijing, Tak Yu Gyoung, Berman Benjamin P, Farnham Peggy J
Abstract excerpt
Colorectal cancer (CRC) is a leading cause of cancer-related deaths in the United States. Genome-wide association studies (GWAS) have identified single nucleotide polymorphisms (SNPs) associated with increased risk for CRC. A molecular understanding of the functional consequences of this genetic variation has been complicated because each GWAS SNP is a surrogate for hundreds of other SNPs, most of which are...
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