Article
Alterations in KLRB1 gene expression and a Scandinavian multiple sclerosis association study of the KLRB1 SNP rs4763655.
European journal of human genetics : EJHG - 1 Oct 2011
Søndergaard Helle Bach, Sellebjerg Finn, Hillert Jan, Olsson Tomas, Kockum Ingrid, Lindén Magdalena, Mero Inger-Lise, Myhr Kjell-Morten, Celius Elisabeth G, Harbo Hanne F, Christensen Jeppe Romme, Börnsen Lars, Sørensen Per Soelberg, Oturai Annette Bang
Abstract excerpt
Multiple sclerosis (MS) is a complex autoimmune disease affecting genetically susceptible individuals. A genome-wide association study performed by the International MS Genetics Consortium identified several putative susceptibility genes; among these, the KLRB1 gene is represented by the single-nucleotide polymorphism rs4763655. We could confirm a marginally significant association between rs4763655 and MS...
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