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Genome Shuffling and Gentamicin-Resistance to Improve ε-Poly-L-Lysine Productivity of Streptomyces albulus W-156.

Applied biochemistry and biotechnology - 1 Dec 2016

Wang Liang, Chen Xusheng, Wu Guangyao, Zeng Xin, Ren Xidong, Li Shu, Tang Lei, Mao Zhonggui

Abstract excerpt

Genome shuffling has been a recently effective method for screening the desirable phenotypes of industrial strains. Here, we combined genome shuffling and gentamicin resistance to improve the production of ε-poly-L-lysine in Streptomyces albulus W-156. Five starting mutants with higher ε-poly-L-lysine (ε-PL) productivities were firstly obtained by atmospheric and room temperature plasma (ARTP) mutagenesis. After...

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PMID: 27422534
DOI: 10.1007/s12010-016-2190-9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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