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Article

Genome shuffling of Streptomyces gilvosporeus for improving natamycin production.

Journal of agricultural and food chemistry - 13 Jun 2012

Luo Jian-Mei, Li Jian-Shu, Liu Dan, Liu Feng, Wang Yan-Ting, Song Xin-Ran, Wang Min

Abstract excerpt

Improvement of natamycin production by Streptomyces gilvosporeus ATCC 13326 was performed by recursive protoplast fusion in a genome-shuffling format. After four rounds of genome shuffling, the best producer, GS 4-21, with genetic stability was obtained and its production of natamycin reached 4.69 ± 0.05 g/L in shaking flask after 96 h cultivation, which was increased by 97.1% and 379% in comparison with the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 22607399
DOI: 10.1021/jf300663w

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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