Article
Connecting Microbial Genotype with Phenotype in the Omics Era.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2020
Yang Yongfu, Qiu Mengyu, Yang Qing, Wang Yu, Wei Hui, Yang Shihui
Abstract excerpt
Although rational design-based metabolic engineering has been applied widely to obtain promising microbial biocatalysts, conventional strategies such as adaptive laboratory evolution (ALE) and mutagenesis are still efficient approaches to improve microorganisms for exceptional features such as a broad spectrum of substrate utilization, robustness of cell growth, as well as high titer, yield, and productivity of...
Topics
- Bacteria
- Computational Biology
- DNA, Bacterial
- DNA, Complementary
- Directed Molecular Evolution
- Genome, Bacterial
- Genomics
- Genotype
- Mutagenesis
- Mutation
- Phenotype