Comprehensive study of early features in spinocerebellar ataxia 2: delineating the prodromal stage of the disease.

doi:10.1007/s12311-014-0574-3

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Article

Comprehensive study of early features in spinocerebellar ataxia 2: delineating the prodromal stage of the disease.

Cerebellum (London, England) - 1 Oct 2014

Velázquez-Pérez Luis, Rodríguez-Labrada Roberto, Cruz-Rivas Edilia M, Fernández-Ruiz Juan, Vaca-Palomares Israel, Lilia-Campins Jandy, Cisneros Bulmaro, Peña-Acosta Arnoy, Vázquez-Mojena Yaimeé, Diaz Rosalinda, Magaña-Aguirre Jonathan J, Cruz-Mariño Tania, Estupiñán-Rodríguez Annelié, Laffita-Mesa José M, González-Piña Rigoberto, Canales-Ochoa Nalia, González-Zaldivar Yanetza

Abstract excerpt

The prodromal phase of spinocerebellar ataxias (SCAs) has not been systematically studied. Main findings come from a homogeneous SCA type 2 (SCA2) population living in Cuba. The aim of this study was to characterize extensively the prodromal phase of SCA2 by several approaches. Thirty-seven non-ataxic SCA2 mutation carriers and its age- and sex-matched controls underwent clinical assessments, including...

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PMID: 24906824
DOI: 10.1007/s12311-014-0574-3

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