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Article

Genetic Variants in the p14ARF/MDM2/TP53 Pathway Are Associated with the Prognosis of Esophageal Squamous Cell Carcinoma Patients Treated with Radical Resection.

PloS one - 1 Jan 2016

Li Jing, Tang Yang, Huang Liu, Yu Qianqian, Hu Guangyuan, Yuan Xianglin

Abstract excerpt

The p14ARF/MDM2/ TP53 pathway is known to play an important role in tumor progression by cell cycle control, although the association between this pathway and the prognosis of esophageal squamous cell carcinoma (ESCC) is unclear. In this study, we explored the association between genetic variants in the p14ARF/MDM2/TP53 pathway and prognosis in ESCC patients with radical resection. 124 ESCC patients with radical...

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Share to Carcinoma, Squamous Cell
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Proto-Oncogene Proteins c-mdm2

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Source

Open in PubMed Open full text

Identifiers

PMID: 27414035
DOI: 10.1371/journal.pone.0158613
PMCID: PMC4944974

Genes

MDM2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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