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Article

Truncating and missense PPM1D mutations in early-onset and/or familial/hereditary prostate cancer patients.

Genes, chromosomes & cancer - 1 Dec 2016

Cardoso Marta, Paulo Paula, Maia Sofia, Teixeira Manuel R

Abstract excerpt

Truncating activating mutations in the last exon of PPM1D have been described in patients with breast, ovarian, colorectal and non-small cell lung cancer, but recent data indicate that they may be associated with previous chemotherapy. In this study we evaluated the prevalence of PPM1D mutations in white blood cells (WBC) of 462 patients with early-onset and/or familial/hereditary prostate cancer (PrCa) by...

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PMID: 27401275
DOI: 10.1002/gcc.22393

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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