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Manganese Superoxide Dismutase Expression Regulates the Switch Between an Epithelial and a Mesenchymal-Like Phenotype in Breast Carcinoma.

Antioxidants & redox signaling - 20 Aug 2016

Loo Ser Yue, Hirpara Jayshree L, Pandey Vijay, Tan Tuan Zea, Yap Celestial T, Lobie Peter E, Thiery Jean Paul, Goh Boon Cher, Pervaiz Shazib, Clément Marie-Véronique, Kumar Alan Prem

Abstract excerpt

AIM: Epithelial-mesenchymal transition (EMT) is characterized by the acquisition of invasive fibroblast-like morphology by epithelial cells that are highly polarized. EMT is recognized as a crucial mechanism in cancer progression and metastasis. In this study, we sought to assess the involvement of manganese superoxide dismutase (MnSOD) during the switch between epithelial-like and mesenchymal-like phenotypes in...

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Identifiers

PMID: 27400860
DOI: 10.1089/ars.2015.6524
PMCID: PMC4991580

Genes

MET

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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