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Article

Conditional radioresistance of Tet-inducible manganese superoxide dismutase bone marrow stromal cell lines.

Radiation research - 1 Aug 2013

Epperly Michael W, Chaillet J Richard, Kalash Ronny, Shaffer Ben, Goff Julie, Franicola Darcy, Zhang Xichen, Dixon Tracy, Houghton Frank, Wang Hong, Berhane Hebist, Romero Cynthia, Kim Jee-Hong, Greenberger Joel S

Abstract excerpt

Mitochondrial targeted manganese superoxide dismutase is a major antioxidant enzyme, the levels of which modulate the response of cells, tissues and organs to ionizing irradiation. We developed a Tet-regulated MnSOD mouse (MnSOD(tet)) to examine the detailed relationship between cellular MnSOD concentration and radioresistance and carried out in vitro studies using bone marrow culture derived stromal cell lines...

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Identifiers

PMID: 23862693
DOI: 10.1667/RR3177.1
PMCID: PMC3783950

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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