Article
Retinoblastoma-associated protein 140 as a candidate for a novel etiological gene to hypertension.
Clinical and experimental hypertension (New York, N.Y. : 1993) - 1 Jan 2000
Crespo Kimberley, Ménard Annie, Deng Alan Y
Abstract excerpt
Gene discovery in animal models may lead to the revelation of therapeutic targets for essential hypertension as well as mechanistic insights into blood pressure (BP) regulation. Our aim was to identify a disease-causing gene for a component of polygenic hypertension contrasting inbred hypertensive Dahl salt-sensitive (DSS) and normotensive Lewis rats. The chromosome segment harboring a quantitative trait locus...
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