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Article

Novel genes as primary triggers for polygenic hypertension.

Journal of hypertension - 1 Jan 2012

Chauvet Cristina, Ménard Annie, Xiao Chunjie, Aguila Benjamin, Blain Marilyne, Roy Julie, Deng Alan Y

Abstract excerpt

OBJECTIVES: The discovery of causative genes leading to hypertension in animal models can reveal new mechanistic insights into blood pressure (BP) regulations. Previously, we isolated segments that harbor BP quantitative trait loci (QTLs) on rat chromosome 10 as defined by congenic strains made from crosses of inbred hypertensive Dahl salt-sensitive (DSS) and normotensive Lewis rats. The aim of the current study...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 22124177
DOI: 10.1097/HJH.0b013e32834dddb1

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