Association between C3435T polymorphism of MDR1 gene and the incidence of drug-resistant epilepsy in the population of Polish children.

doi:10.1186/s12993-016-0106-z

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Article

Association between C3435T polymorphism of MDR1 gene and the incidence of drug-resistant epilepsy in the population of Polish children.

Behavioral and brain functions : BBF - 8 Jul 2016

Stasiołek Mariusz, Romanowicz Hanna, Połatyńska Katarzyna, Chamielec Maciej, Skalski Dominik, Makowska Marianna, Smolarz Beata

Abstract excerpt

PURPOSE: Epilepsy is a disease of neurological character. Approximately one third of epileptic patients demonstrate a drug-resistant phenotype, which is associated with the development of drug-resistant epilepsy. The multidrug resistance protein 1 and glycoprotein P, encoded by MDR1, play a significant role in the transmembrane transport of anti-epileptic agents. Single nucleotide polymorphism C3435T (rs1045642)...

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PMID: 27391700
DOI: 10.1186/s12993-016-0106-z
PMCID: PMC4938960

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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