Article
Multidrug resistance 1 (MDR1) 3435C/T genotyping in childhood drug-resistant epilepsy.
Brain & development - 1 Feb 2014
Saygi Semra, Alehan Fusun, Atac Fatma Belgin, Erol Ilknur, Verdi Hasibe, Erdem Remzi
Abstract excerpt
INTRODUCTION: A mutation at nucleotide position 3435 in exon 26 of the multidrug resistance 1 (MDR1) gene is the most frequently studied polymorphism in relation to multidrug resistance. However, there are conflicting data as to whether the CC or TT genotype of the 3435C>T polymorphism is associated with drug resistance. METHODS AND RESULTS: We investigated the association between this polymorphism in...
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