Article
Association of MDR1 gene C3435T polymorphism with childhood intractable epilepsy: a meta-analysis.
Journal of neural transmission (Vienna, Austria : 1996) - 1 Jul 2014
Sun Guilian, Sun Xue, Guan Limei
Abstract excerpt
Drug-resistant epilepsy is also referred to as intractable, medically refractory, or pharmacoresistant epilepsy. Approximately, one-third of patients with epilepsy have recurrent seizures despite therapy. Multidrug resistance 1 (MDR1) gene may play a role in drug-resistance in epilepsy. To assess the association between MDR1 C3435T polymorphism and the response to anticonvulsants in childhood intractable...
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