Article
Multidrug resistance 1 (MDR1) gene polymorphisms in childhood drug-resistant epilepsy.
Journal of child neurology - 1 Dec 2010
Alpman Asude, Ozkinay Ferda, Tekgul Hasan, Gokben Sarenur, Pehlivan Sacide, Schalling Martin, Ozkinay Cihangir
Abstract excerpt
Despite considerable progress in the pharmacotherapy of epilepsy, more than 30% of patients are reported to be resistant to antiepileptic drugs. Multidrug resistance 1 (MDR1) gene could play a role in drug resistance in epilepsy. In this study, the authors investigated the association between the MDR1 gene polymorphisms, C3435T and G2677AT, and drug resistance epilepsy by using polymerase chain...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
