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Article

CYP3A5*3 and C3435T MDR1 polymorphisms in prognostication of drug-resistant epilepsy in children and adolescents.

BioMed research international - 1 Jan 2013

Emich-Widera Ewa, Likus Wirginia, Kazek Beata, Niemiec Paweł, Balcerzyk Anna, Sieroń Aleksander L, Zak Iwona

Abstract excerpt

Drug-resistant epilepsies still remain one of the most profound problems of contemporary epileptology. Several mechanisms of drug resistance are possible; among them, genetic factors have a prominent place. Much importance is attached to genes, which encode enzymes that metabolize antiepileptic drugs CYP 3A, which belong to the family of cytochromes P450 and the genome of multidrug resistance, such as multidrug...

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Identifiers

PMID: 23984379
DOI: 10.1155/2013/526837
PMCID: PMC3747339

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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