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Article

Significance of TET2 mutations in myeloid and lymphoid neoplasms.

[Rinsho ketsueki] The Japanese journal of clinical hematology - 1 Jun 2016

Chiba Shigeru

Abstract excerpt

The TET2 gene is an epigenetic regulator. Loss-of-function mutations of TET2 are found in a variety of blood cancers in both myeloid and lymphoid lineages. Meanwhile, clonal blood cells carrying leukemia-driver mutations have been detected in significant proportions of different cohorts without blood cancers. Amongst these driver mutations, those in the TET2 gene are second/third most frequent. The presence of...

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Source

Identifiers

PMID: 27384850
DOI: 10.11406/rinketsu.57.715

Genes

TET2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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