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Article

High expression of MnSOD promotes survival of circulating breast cancer cells and increases their resistance to doxorubicin.

Oncotarget - 2 Aug 2016

Fu Afu, Ma Shijun, Wei Na, Tan Blanche Xiao Xuan, Tan Ern Yu, Luo Kathy Qian

Abstract excerpt

Understanding the survival mechanism of metastatic cancer cells in circulation will provide new perspectives on metastasis prevention and also shed new light on metastasis-derived drug resistance. In this study, we made it feasible to detect apoptosis of circulating tumor cells (CTCs) in real-time by integrating a fluorescence resonance energy transfer (FRET)-based caspase sensor into one in vitro microfluidic...

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Identifiers

PMID: 27384484
DOI: 10.18632/oncotarget.10360
PMCID: PMC5226580

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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