Article

Isosceles Trapezoidal Spiral Microchannel for Separation of Large particles and Giant Cancer cells

2023-04-24

Abstract excerpt

<h4>Background: </h4> Polyploid giant cancer cells (PGCCs) contribute to the genetic heterogeneity and evolution of tumor cells. To study these cells, they need to be separated from tumor cell populations. However, due to their large size it is challenging to isolate them. Currently used methods, such as fluorescence-activated cell sorting (FACS) require fluorescent labeling which impedes reliable downstream analy...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 83840ee8-8851-5c6e-b6c2-639ad8f767a1
DOI: 10.21203/rs.3.rs-2816407/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Isosceles Trapezoidal Spiral Microchannel for Separation of Large particles and Giant Cancer cellsDOI 10.21203/rs.3.rs-2816407/v1Read

Microfluidic Isolation of Circulating Tumor Cell Clusters by Size and AsymmetrySemantic proximity Read

Separation of leukocytes from blood using spiral channel with trapezoid cross-section.Semantic proximity Read

Microfluidic techniques for isolation, formation, and characterization of circulating tumor cells and clustersSemantic proximity Read

Size-selective microcavity array for rapid and efficient detection of circulating tumor cells.Semantic proximity Read

Advances in microfluidic platforms for tumor cell phenotyping: from bench to bedside.Semantic proximity Read

Isolation of circulating fetal trophoblasts by a four-stage inertial microfluidic device for single-cell analysis and noninvasive prenatal testingSemantic proximity Read

Characterization of circulating tumor cells in breast cancer patients by spiral microfluidicsSemantic proximity Read

Single-Cell Isolation and Patient-Derived Organoid Generation Using the Pala™ Single Cell Dispenser with Cancer Cell Lines Spiked into Blood as a Circulating Tumour Cell Model: A Platform for Precision Oncology and Drug DiscoverySemantic proximity Read

An integrated microfluidic chip for the capture, migration and molecular phenotyping of single circulating tumor cells.Semantic proximity Read

Rapid Microfluidic Formation of Uniform Patient-Derived Breast Tumor SpheroidsSemantic proximity Read

Development of a Rare Cell Fractionation Device: Application for Cancer DetectionSemantic proximity Read

Quantitative Magnetic Deflection Enables Continuous‐Flow Separation of Cell SubtypesSemantic proximity Read