Article
Subclinical dose irradiation triggers human breast cancer migration via mitochondrial reactive oxygen species
8 Jul 2024
Abstract excerpt
Abstract Background Despite technological advances in radiotherapy, cancer cells at the tumor margin and in diffusive infiltrates can receive subcytotoxic doses of photons. Even if only a minority of cancer cells are concerned, phenotypic consequences could be important considering that mitochondrial DNA (mtDNA) is a primary target of radiation and that damage to mtDNA can persist. In turn, mitochondrial...
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