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Article

Rapid identification of the NAT2 genotype in tuberculosis patients by multicolor melting curve analysis.

Pharmacogenomics - 1 Jul 2016

Hu Yanjie, Chen Suting, Yu Xia, Dai Guangming, Dong Lingling, Li Yunxu, Zhao Liping, Huang Hairong

Abstract excerpt

AIM: NAT2 genotype is an indicator for isoniazid dosage adjusting for tuberculosis treatment. Multicolor melting curve analysis (MMCA) was evaluated as a potential method for NAT2 genotyping. MATERIALS & METHODS: 352 blood samples were analyzed by MMCA kit (Zeesan Biotech Co., Xiamen, China) targeting NAT2 SNPs at T341C, C481T, G590A and G857A, and direct sequencing was used as control. RESULTS: The sensitivity,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 27377479
DOI: 10.2217/pgs-2016-0026

Genes

NAT2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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