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Article

Inter-individual variability and genetic influences on cytokine responses to bacteria and fungi.

Nature medicine - 1 Aug 2016

Li Yang, Oosting Marije, Deelen Patrick, Ricaño-Ponce Isis, Smeekens Sanne, Jaeger Martin, Matzaraki Vasiliki, Swertz Morris A, Xavier Ramnik J, Franke Lude, Wijmenga Cisca, Joosten Leo A B, Kumar Vinod, Netea Mihai G

Abstract excerpt

Little is known about the inter-individual variation of cytokine responses to different pathogens in healthy individuals. To systematically describe cytokine responses elicited by distinct pathogens and to determine the effect of genetic variation on cytokine production, we profiled cytokines produced by peripheral blood mononuclear cells from 197 individuals of European origin from the 200 Functional Genomics...

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Identifiers

PMID: 27376574
DOI: 10.1038/nm.4139
PMCID: PMC5084084

Genes

GOLM1
NAA35

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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