Article
Correlation of NPM1 Type A Mutation Burden With Clinical Status and Outcomes in Acute Myeloid Leukemia Patients With Mutated NPM1 Type A.
Annals of laboratory medicine - 1 Sept 2016
Jo Su Yeon, Park Sang Hyuk, Kim In Suk, Yi Jongyoun, Kim Hyung Hoi, Chang Chulhun L, Lee Eun Yup, Cho Young Uk, Jang Seongsoo, Park Chan Jeoung, Chi Hyun Sook
Abstract excerpt
BACKGROUND: Nucleophosmin gene (NPM1) mutation may be a good molecular marker for assessing the clinical status and predicting the outcomes in AML patients. We evaluated the applicability of NPM1 type A mutation (NPM1-mutA) quantitation for this purpose. METHODS: Twenty-seven AML patients with normal karyotype but bearing the mutated NPM1 were enrolled in the study, and real-time quantitative PCR of NPM1-mutA was...
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