Prevalence and Clinical Significance of FLT3 Mutation Status in Acute Myeloid Leukemia Patients: A Multicenter Study.

doi:10.1016/j.arcmed.2016.06.003

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Article

Prevalence and Clinical Significance of FLT3 Mutation Status in Acute Myeloid Leukemia Patients: A Multicenter Study.

Archives of medical research - 1 Apr 2016

Cuervo-Sierra Jorge, Jaime-Pérez José Carlos, Martínez-Hernández Ramón A, García-Sepúlveda Ricardo D, Sánchez-Cárdenas Mónica, Gómez-Almaguer David, Ortíz-López Rocío, Villarreal-Villarreal César D, Ruiz-Arguelles Guillermo J, Ruiz-Delgado Guillermo, Lutz-Presno Julia, Garcés-Eisele Javier, Ignacio-Ibarra Gregorio, Muciño-Hernández Gabriel, Arana-Trejo Rosa M, Jiménez-Mejia Angélica M, Vásquez-Palacio Gonzalo

Abstract excerpt

BACKGROUND AND AIMS: FLT3-ITD mutations in acute myeloid leukemia (AML) are associated with a poor prognosis. In Latin America, little epidemiological data exist about these mutations and their influence on clinical evolution and prognosis. Standardization and well-established clinical correlation make FLT3 mutational analysis by molecular methods an invaluable tool to decide among treatment options and to...

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PMID: 27373815
DOI: 10.1016/j.arcmed.2016.06.003

Genes

FLT3

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