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Article

p62 modulates the intrinsic signaling of UVB-induced apoptosis.

Journal of dermatological science - 1 Sept 2016

Ito Sachiko, Kimura Shintaro, Warabi Eiji, Kawachi Yasuhiro, Yamatoji Masanobu, Uchida Fumihiko, Ishibashi-Kanno Naomi, Yamagata Kenji, Hasegawa Shogo, Shoda Junichi, Tabuchi Katsuhiko, Sakai Satoshi, Bukawa Hiroki, Sekido Mitsuru, Yanagawa Toru

Abstract excerpt

BACKGROUND: UVB radiation is the main source of sunburn and skin cancers. Apoptosis eliminates photodamaged cells, and is thus important for preventing epidermal carcinogenesis. The cytoplasmic regulatory protein p62/A170/sequestosome 1 (p62) molecule is involved in a variety of cellular and signaling pathways. p62 is known to be and important in autophagy, but its role in UVB-induced apoptosis remains to be...

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Identifiers

PMID: 27368125
DOI: 10.1016/j.jdermsci.2016.05.005

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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