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Article

Autophagy Controls p38 Activation to Promote Cell Survival under Genotoxic Stress

5 Dec 2012

Abstract excerpt

Deregulated cell survival under carcinogen-induced genotoxic stress is vital for cancer development. One of the cellular processes critical for cell survival under metabolic stress and energy starvation is autophagy, a catabolic process involved in capture and delivery of cytoplasmic components to lysosomes for degradation. However, the role of autophagy following carcinogen-induced genotoxic stress remains...

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PMID: 23212914
DOI: 10.1074/jbc.m112.415224

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