Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Fas-independent apoptosis induced by UVC in p53-mutated human epithelial tumor A431 cells through activation of caspase-8 and JNK/SAPK.

Journal of radiation research - 1 Jun 2001

Hama-Inaba H, Choi K H, Wang B, Haginoya K, Yamada T, Hayata I, Ohyama H

Abstract excerpt

A431 cells/UVC-induced apoptosis/Caspase 8/Fas/JNK/PAPK. We previously observed that p53-mutated human epithelial tumor A431 cells underwent apoptosis after ultraviolet C (UVC) irradiation through the caspases-8 and -3 pathway. Fas/FasL is known to initiate apoptosis in several cell lines via caspase-8 activation. Then, to determine if Fas/FasL mediates apoptosis in A431. we investigated Fas expression and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Caspase 8
Share to Caspase 9

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Caspases

Share to fas Receptor

Share to JNK Mitogen-Activated Protein Kinases

Share to MAP Kinase Kinase 4

Share to Mitogen-Activated Protein Kinase Kinases

Share to Ultraviolet Rays

Source

Identifiers

PMID: 11599886
DOI: 10.1269/jrr.42.201

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Fas-independent apoptosis induced by UVC in p53-mutated human epithelial tumor A431 cells through activation of caspase-8 and JNK/SAPK.PMID 11599886Read ↗

Molecular aspects of ultraviolet radiation-induced apoptosis in the skin.Semantic proximity Read ↗

p62 modulates the intrinsic signaling of UVB-induced apoptosis.Semantic proximity Read ↗

Proliferation-dependent induction of apoptosis by the retinoid CD437 in p53-mutated keratinocytes.Semantic proximity Read ↗

Role of apoptosis in basal cell and squamous cell carcinoma formation.Semantic proximity Read ↗

Cell proliferation and DNA breaks are involved in ultraviolet light-induced apoptosis in nucleotide excision repair-deficient Chinese hamster cells.Semantic proximity Read ↗

A caspase-resistant mutant of PKC-delta protects keratinocytes from UV-induced apoptosis.Semantic proximity Read ↗

Retinoic Acid Increases the Expression of p53 and Proapoptotic Caspases and Sensitizes Keratinocytes to ApoptosisSemantic proximity Read ↗

Protective Effect of Cyanidin-3-O-Glucoside against Ultraviolet B Radiation-Induced Cell Damage in Human HaCaT KeratinocytesSemantic proximity Read ↗

Relationship of p53 mutations to epidermal cell proliferation and apoptosis in human UV-induced skin carcinogenesis.Semantic proximity Read ↗

Ras mutation promotes p53 activation and apoptosis of skin keratinocytes.Semantic proximity Read ↗

Ultraviolet B-induced apoptosis of human skin fibroblasts involves activation of caspase-8 and -3 with increased expression of vimentinSemantic proximity Read ↗

MiR-23a regulates DNA damage repair and apoptosis in UVB-irradiated HaCaT cellsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.