Article
The Wnt pathway limits BMP signaling outside of the germline stem cell niche in Drosophila ovaries.
Developmental biology - 1 Sept 2016
Mottier-Pavie Violaine I, Palacios Victor, Eliazer Susan, Scoggin Shane, Buszczak Michael
Abstract excerpt
The mechanisms that modulate and limit the signaling output of adult stem cell niches remain poorly understood. To gain further insights into how these microenvironments are regulated in vivo, we performed a candidate gene screen designed to identify factors that restrict BMP signal production to the cap cells that comprise the germline stem cell (GSC) niche of Drosophila ovaries. Through these efforts, we found...
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