Article

Canonical Wnt signaling promotes formation of somatic permeability barrier for proper germ cell differentiation

2022-02-16

Abstract excerpt

Morphogen-mediated signaling is critical for proper organ development and stem cell function, and well-characterized mechanisms spatiotemporally limit the expression of ligands, receptors, and ligand-binding cell-surface glypicans. Here, we show that in the developing Drosophila ovary, canonical Wnt signaling promotes the formation of somatic escort cells (ECs) and their protrusions, which establish a physical pe...

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Literature Corpus work: 8c604b86-f7b6-51ce-9f0a-50cebd2f7768
DOI: 10.1101/2022.02.15.480616

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