Article
Wingless signaling regulates the maintenance of ovarian somatic stem cells in Drosophila.
Development (Cambridge, England) - 1 Jul 2003
Song Xiaoqing, Xie Ting
Abstract excerpt
Identifying the signals involved in maintaining stem cells is critical to understanding stem cell biology and to using stem cells in future regenerative medicine. In the Drosophila ovary, Hedgehog is the only known signal for maintaining somatic stem cells (SSCs). Here we report that Wingless (Wg) signaling is also essential for SSC maintenance in the Drosophila ovary. Wg is expressed in terminal filament and cap...
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