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Article

Germline stem cells anchored by adherens junctions in the Drosophila ovary niches.

Science (New York, N.Y.) - 7 Jun 2002

Song Xiaoqing, Zhu Chun-Hong, Doan Chuong, Xie Ting

Abstract excerpt

How stem cells are recruited to and maintained in their niches is crucial to understanding their regulation and use in regenerative medicine. Here, we demonstrate that DE-cadherin-mediated cell adhesion is required for anchoring germline stem cells (GSCs) in their niches in the Drosophila ovary. Two major components of this adhesion process, DE-cadherin and Armadillo/beta-catenin, accumulate at high levels in the...

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PMID: 12052957
DOI: 10.1126/science.1069871

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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