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Article

Presenilin E318G variant and Alzheimer's disease risk: the Cache County study.

BMC genomics - 29 Jun 2016

Hippen Ariel A, Ebbert Mark T W, Norton Maria C, Tschanz JoAnn T, Munger Ronald G, Corcoran Christopher D, Kauwe John S K

Abstract excerpt

BACKGROUND: Alzheimer's disease is the leading cause of dementia in the elderly and the third most common cause of death in the United States. A vast number of genes regulate Alzheimer's disease, including Presenilin 1 (PSEN1). Multiple studies have attempted to locate novel variants in the PSEN1 gene that affect Alzheimer's disease status. A recent study suggested that one of these variants, PSEN1 E318G...

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Share to Alzheimer Disease
Share to Apolipoprotein E4

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Epistasis, Genetic

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Share to Mutation, Missense

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Share to Presenilin-1

Source

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Identifiers

PMID: 27357204
DOI: 10.1186/s12864-016-2786-z
PMCID: PMC4943516

Genes

PSEN1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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