Article
A cluster of Epoetin-associated pure red cell aplasia: clinical features and the possible association of HLA-DRB1*12:02.
Pharmacogenomics - 1 Jul 2016
Tan Chuen Wen, Tan-Koi Wei-Chuen, Ng Jennifer, Chan Choong Meng, Hwang William Ying Khee
Abstract excerpt
Antibody-mediated pure red cell aplasia is a rare but serious complication in chronic kidney disease patients receiving recombinant human erythropoietin (r-HuEpo). Between April 2012 and May 2013, eight such cases were reported in our institution. Their clinical features were reviewed and their HLA alleles were compared with those of healthy controls. All patients were exposed to epoetin alfa (Eprex®) with...
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