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Article

T cell clonal expansion and STAT3 mutations: a characteristic feature of acquired chronic T cell-mediated pure red cell aplasia.

International journal of hematology - 1 Jun 2022

Kawakami Fumihiro, Kawakami Toru, Yamane Taku, Maruyama Masae, Kobayashi Jun, Nishina Sayaka, Sakai Hitoshi, Higuchi Yumiko, Hamanaka Kazutoshi, Hirokawa Makoto, Nakao Shinji, Nakazawa Hideyuki, Ishida Fumihiro

Abstract excerpt

Acquired chronic pure red cell aplasia (PRCA) develops idiopathically or in association with other medical conditions, including T cell large granular lymphocytic leukemia (T-LGLL) and thymoma. T cell dysregulation is considered a cardinal pathogenesis of PRCA, but genetic-phenotypic associations in T cell abnormalities are largely unclear. We evaluated an extended cohort of 90 patients with acquired PRCA,...

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Share to CD8-Positive T-Lymphocytes
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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Share to Receptors, Antigen, T-Cell

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Source

Identifiers

PMID: 35275353
DOI: 10.1007/s12185-022-03310-2

Genes

STAT3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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T cell clonal expansion and STAT3 mutations: a characteristic feature of acquired chronic T cell-mediated pure red cell aplasia.PMID 35275353Read ↗

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