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Article

Case-control study of the association between select HLA genes and anti-erythropoietin antibody-positive pure red-cell aplasia.

Pharmacogenomics - 1 Feb 2008

Fijal Bonnie, Ricci Deborah, Vercammen Els, Palmer Peter A, Fotiou Fotis, Fife Daniel, Lindholm Anders, Broderick Erin, Francke Stephan, Wu Xiaodong, Colaianne James, Cohen Nadine

Abstract excerpt

AIMS: Antibody (Ab)-positive pure red-cell aplasia (PRCA) is a very rare but serious adverse event associated with recombinant human erythropoietin treatment (4.1 reports per 100,000 patient-years) in which patients produce antibodies to recombinant and endogenous erythropoietin, halting red blood cell production. In a previous case series, four Thai subjects with chronic kidney disease and Ab-positive PRCA were...

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Identifiers

PMID: 18370845
DOI: 10.2217/14622416.9.2.157

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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