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Article

The association of anti-r-HuEpo-associated pure red cell aplasia with HLA-DRB109-DQB10309.

Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association - 1 May 2009

Praditpornsilpa Kearkiat, Kupatawintu Pawinee, Mongkonsritagoon Wichean, Supasyndh Ouppatham, Jootar Saengsuree, Intarakumthornchai Tanin, Pongskul Cholatip, Prasithsirikul Wisit, Achavanuntakul Bunlersak, Ruangkarnchanasetr Prajej, Laohavinij Sudsawat, Eiam-Ong Somchai

Abstract excerpt

BACKGROUND: Anti-r-HuEpo associated PRCA developed in patients received subcutaneous injection of r-HuEpo for treatment of renal anemia in chronic kidney disease. This adverse immunological effect of r-HuEpo causes sudden loss of r-HuEpo efficacy, low circulating reticulocyte count and bone marrow biopsy shows an absence of erythroid precursor cells with normal cell population of non-erythroid lineage. There are...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 18689790
DOI: 10.1093/ndt/gfn450

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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