Article
[Acquired pure red cell aplasia].
[Rinsho ketsueki] The Japanese journal of clinical hematology - 1 Jan 2026
Nakazawa Hideyuki
Abstract excerpt
Acquired pure red cell aplasia (PRCA) is a bone marrow failure syndrome characterized by anemia, reticulocytopenia, and erythroid hypoplasia in the marrow that mostly affects older adults. Underlying T-cell dysregulation, often associated with clonality and/or STAT3 mutation among CD8+T-cells, provides a rationale for directed immunosuppressive therapies such as cyclosporin in the three most frequent disease...
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