Article
A Genetic Variant rs1020760at NFKB1 is Associated with Clinical Features of Psoriasis Vulgaris in a Han Chinese Population.
Annals of human genetics - 1 Jul 2016
Wang Wenjun, Zhu Zhengwei, Zhu Caihong, Zheng Xiaodong, Zuo Xianbo, Chen Gang, Zhou Fusheng, Liang Bo, Tang Huayang, Wang Zaixing, Zhang Xuejun, Sun Liangdan
Abstract excerpt
Psoriasis vulgaris is a chronic inflammatory skin disease associated with complex genetic susceptibility. Recently, we identified a single-nucleotide variant rs1020760 at NFKB1 significantly associated with psoriasis in a Han Chinese population in deep analysis of exome and targeted sequencing (P = 1.76 × 10(-8) ). To investigate the potential association between rs1020760 and phenotypes of psoriasis vulgaris, we...
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